Perforation due to stent misplacement is uncommon with EUS guidance in expert hands. However, rapid decompression of a large collection (particularly if the wall is not fully mature and adherent) may lead to dehiscence of the cyst wall from the stomach or duodenum and a clinically significant leak. This is less likely when a LAMS is used. ERCP and transpapillary drainage is associated with the additional risk of pancreatitis.
Conclusion
Endoscopy is well established as an important tool in the armamentarium of the multidisciplinary team managing pancreatic fluid collections. Despite improvements in technique and devices reflecting the complexity of the disease process, endoscopic drainage remains associated with significant morbidity and potential for mortality and careful patient selection and assesment is mandatory.
References
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