Recent Advances in the Pathogenesis and Treatment of Kidney Diseases. Группа авторов. Читать онлайн. Newlib. NEWLIB.NET

Автор: Группа авторов
Издательство: Ingram
Серия: Contributions to Nephrology
Жанр произведения: Медицина
Год издания: 0
isbn: 9783318063509
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Membrane proteins CD36, SR-BI (lipoprotein receptor) Gp60 (albumin receptor) PV-1 P-glycoprotein MMP-1 MMP-2 uPAR Ion channels Transient receptor potential cation L-type Ca2+ KATP Ca2+ pumps Img

      Albumin Transportation through Caveolae

      Glomerular Endothelial Cells

      Glomerular Epithelial Cells

      Albumin particles have been shown to pass through abnormal slit membrane in cases of decreased nephrin expression between the foot processes of glomerular epithelial cells (podocytes). However, in cases of nephrotic syndrome, foot processes are dramatically effaced and the number of slit membranes in the gap is drastically decreased; this provides a useful model to study the intracellular trafficking pathways by which albumin traverses through glomerular epithelial cells.