Acute Kidney Injury - Basic Research and Clinical Practice. Группа авторов

is a complex syndrome with specific “endotypes” and pathophysiologies and no single definition will be perfect. Nonetheless, early standard recognition of AKI is crucial, since no specific therapeutic intervention has been demonstrated to be effective and standardized epidemiology and benchmarks are required. The KDIGO definition relies on changes in SCr and UO: 2 universally available and inexpensive markers that although imperfect represent a fundamental step forward in the field of critical care nephrology that has allowed the physicians to better identify AKI patients ahead of time. The KDIGO classification has significantly increased our insights into the epidemiology of the AKI syndrome both in children and adult critically ill patients and allowed clinicians and researchers to communicate in this field. A neonatal KDIGO is currently available and validated in order to definitely conclude the complex pathway of AKI definition in all populations and ages (AKI, pAKI, nAKI). By using a common language, studies and trials can be now compared.

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