Complications in Equine Surgery. Группа авторов. Читать онлайн. Newlib. NEWLIB.NET

Автор: Группа авторов
Издательство: John Wiley & Sons Limited
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Жанр произведения: Биология
Год издания: 0
isbn: 9781119190158
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target="_blank" rel="nofollow" href="#ulink_4f538a8a-feff-526d-a21e-203c593c100c">Figure 10.1 Loosely arranged cancellous bone graft in blood‐soaked sponge following collection from tuber coxae.

      The bone graft material should be lightly packed into the recipient site to allow for appropriate oxygenation of the graft and to reduce mechanical damage to the cells [1, 10]. Osteogenesis occurs as a result of the activity of viable osteoblasts on the surface of the bone graft. Loosely arranged bone grafts are more desirable due to the greater surface area created, with more living cells available resulting in greater osteogenic activity. Avoiding dehydration and compaction of the bone graft results in a greater number of surviving cells and improved viability of the graft [8].

       Diagnosis

      Reduced viability of the bone graft may contribute to lack of incorporation of the graft into host tissue, resulting in prolonged fracture repair or increased rate of fracture repair failure. However, lack of viability of the graft itself may not be apparent unless infection of the recipient site occurs or fracture repair failure occurs postoperatively as a result of implant fatigue. Diagnostic imaging (e.g. radiography, ultrasonography or CT) may be utilized to recognize infection or fracture repair failure earlier if indicated based upon clinical signs.

      Monitoring

      Monitoring for host acceptance of the graft involves monitoring for morbidity at the recipient site (e.g. infection) as well as clinical and radiographic evidence of bone healing. Radiographic signs consistent with infection or lack of incorporation of the graft include evidence of malunion of the fracture site or lucency around the implants. Complete integration of the bone graft into host tissue may take years [9]. Autogenous cancellous bone grafting enhances and stimulates bone healing, and utilization of bone grafts in long bone fracture repair should decrease fracture healing time and fracture repair failure as a result of implant fatigue.

      Treatment

      Treatment following reduced viability of a bone graft is typically not necessary unless infection of the recipient site occurs due to lack of adherence to aseptic technique. Aggressive treatment of infection of the graft bed or fracture site is recommended, typically with a combination of local and systemic antibiotic therapy. In addition, revision of the fracture repair and local lavage may be performed.

      Expected outcome

      Lack of incorporation of the bone graft may contribute to prolonged fracture repair as well as infection of the recipient site if aseptic technique is not followed appropriately. In the event of persistent infection, removal of orthopedic implants may be necessary following fracture repair and bone healing.

      Morbidity Associated with Incision at Donor Site

       Definition

      The most common complications associated with the incision for bone graft harvest include incisional infection, seroma, and drainage with peri‐incisional edema [3, ]. Incisional dehiscence may result in osteomyelitis, particularly when the sternum and proximal tibia are used as donor sites [13].

       Risk factors

      Harvest site location

       Pathogenesis

      Case‐specific factors dictate intraoperative access to the donor site, amount of graft material required, as well as other case‐specific factors including pre‐existing soft tissue trauma or decubital ulcers [12, 16, 17].

      Utilization of the sternum as a graft donor site is associated with minor complications, including peri‐incisional edema, serum exudate, and wound dehiscence due to the ventral location and tension [16].

      Incisional dehiscence, which may result in osteomyelitis, is reported, particularly when the sternum and proximal tibia are used as donor sites due to tension and location [13].

       Prevention

      Location of the donor site is selected based upon the location of the surgical site and therefore anesthetic recumbency selected, which dictates intraoperative access to the site and amount of graft material required. While multiple donor sites may supply an adequate quantity of bone graft material, each donor site carries its own risks and benefits in terms of early postoperative sequellae. Donor site selection is made after taking into account the known risks associated with each site as well as case specific factors such as location of the lesion, soft tissue trauma or presence of decubital ulcers. Whenever possible, avoiding sites at greatest risk of complication is recommended (Table 10.1 ).

       Diagnosis

      Incisional infection, seroma, or edema is diagnosed by clinical examination with evidence of drainage or swelling at the incision site.

       Monitoring

      Monitor the graft donor incision site for increased drainage, swelling or dehiscence that may indicate seroma formation or infection. Complete integration of the bone graft into host tissue may take years [9]. Autogenous cancellous bone grafting enhances and stimulates bone healing, and utilization of bone grafts in long bone fracture repair should decrease fracture repair failure as a result of implant fatigue.

       Treatment

      Incisional infection or seroma at the donor site may be treated successfully with facilitated drainage of the incision site and antimicrobial therapy.

       Expected outcome

      Incisional complications, such as incisional infection, seroma, and drainage with peri‐incisional edema or superficial incisional infection, are usually self‐limited and carry a good prognosis [3, 12, 13]. Osteomyelitis is a more serious condition but usually responds well to local debridement and antimicrobial therapy.

Donor Site Advantages Disadvantages
Tuber coxae [2, 23, 17] Provide ample grafting materialGood visualization for surgical approachLow rate of postoperative incisional complicationsRemains the most commonly used donor site Time‐consumingRequires patient in lateral recumbencyDecubital ulcers or soft tissue trauma over the tuber coxae may preclude its use
Sternum [16, 21, 37, 38, 39] Use in cases where patient in dorsal recumbencyReduces risk of pathological fracture associated with harvesting from the tibia and humerusAbsence of skin tension and dependency of this

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