Table of Contents
1 Cover
5 Preface
6 CHAPTER 1: Definitions of Sarcopenia SARCOPENIA: BIRTH AND FIRST STEPS GROWTH AND ADOLESCENCE OF SARCOPENIA MATURITY OF SARCOPENIA: RECENT DEFINITIONS NEW PLAYERS: BONE, FAT, AND MUSCLE THE FRONTIERS: FRAILTY, CACHEXIA, MALNUTRITION THE RESEARCH ARENA SUMMARY REFERENCES
7 CHAPTER 2: Epidemiology of Muscle Mass Loss with Age INTRODUCTION MUSCLE MASS DIFFERENCES AMONG AGE GROUPS CHANGE IN MUSCLE MASS WITH AGING REFERENCES
8 CHAPTER 3: The Role of Mitochondria in Age‐Related Sarcopenia MUSCLES TRANSFORM CHEMICAL ENERGY INTO MECHANICAL ENERGY EVIDENCE THAT MITOCHONDRIAL FUNCTION DECLINES WITH AGING AND ITS CONSEQUENCES ON MUSCLE HEALTH AND FUNCTION CAUSES OF THE DECLINE OF MITOCHONDRIAL MASS AND OXIDATIVE CAPACITY IN AGING SKELETAL MUSCLE ARE AGE‐RELATED CHANGES IN MITOCHONDRIAL FUNCTION AT THE ROOT OF SARCOPENIA? ACKNOWLEDGMENTS REFERENCES
9 CHAPTER 4: Motor Unit Remodeling OVERVIEW OF THE NEUROMUSCULAR SYSTEM AGE‐RELATED MU REMODELING LOSS OF MUSCLE FIBERS REDUCED FIRING CAPACITY OF MUs MECHANISMS OF MU REMODELING FUTURE DIRECTIONS CONCLUSIONS REFERENCES
10 CHAPTER 5: Nutrition, Protein Turnover and Muscle Mass INTRODUCTION EVIDENCES FOR A ROLE FOR NUTRITION IN SARCOPENIA ANABOLIC RESPONSE TO PHYSICAL EXERCISE IN OLDER PERSONS COMBINATION OF NUTRITIONAL AND TRAINING STRATEGIES CONCLUDING REMARKS AND FUTURE DIRECTION REFERENCES
11 CHAPTER 6: Recognizing Persons at Risk for Sarcopenia SARC‐F OTHER SCREENING TESTS FOR SARCOPENIA CONCLUSION DISCLOSURES REFERENCES
12 CHAPTER 7: Adverse Outcomes and Functional Consequences of Sarcopenia INTRODUCTION MORTALITY MOBILITY LIMITATIONS FALLS AND FRACTURES QUALITY OF LIFE METABOLIC CONSEQUENCES SECONDARY SARCOPENIA CONTROVERSIES CONCLUSION REFERENCES
13 CHAPTER 8: A Lifecourse Approach to Sarcopenia INTRODUCTION A LIFECOURSE APPROACH USE OF COHORT STUDIES ACROSS THE LIFECOURSE LIFECOURSE CONSEQUENCES OF SARCOPENIA LIFECOURSE DETERMINANTS OF SARCOPENIA CELLULAR AND MOLECULAR MECHANISMS CONCLUSIONS AND RELEVANCE TO CLINICAL PRACTICE REFERENCES
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