Diabetic Neuropathy. Friedrich A. Gries. Читать онлайн. Newlib. NEWLIB.NET

Автор: Friedrich A. Gries
Издательство: Ingram
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Жанр произведения: Медицина
Год издания: 0
isbn: 9783131606419
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thiazolidindiones. Expert Opin Invest Drug 1997; 6: 1025-40.

      [409] Ferman LM, Simmons DA, Diamond RH. Hepatic failure in a patient taking rosiglitazone. Ann Int Med 2000; 132: 118-21.

      [410] Al-Salman J, Arjomand H, Kemp DG, Mittal M. Hepatocellular injury in a patient recieving rosiglitazone: a case report. Ann Intern Med 2000; 132: 121-4.

      [432] Panzram G. Mortalität und Lebenserwartung des insulinabhängigen Typ 2 Diabetes. Diabetes Dialog 1992; 1: 1-4.

      2 Structure and Function of the Nervous System

      N. E. Cameron and C. J. Mathias

      N. E. Cameron

Overview

      The somatic nervous system is subdivided into motor and sensory components. The motor division is concerned with control of skeletal muscle contraction, and hence of voluntary movement and of posture and reflexes. The somatosensory division is a collection of receptors, tracts, and nuclei that convey the sensations of light touch, vibration, temperature, and pain (nociception) to the consciousness. It also conveys information about movements and position of the body (proprioception and kinesthesia). Somatosensory receptors are found in the skin, muscles, joints, and viscera. In addition to providing sensation, the somatosensory division has a critical role in motor control, through feedback about muscle length and tension, joint position, velocity of muscle and limb movement, and contact with external surfaces. The basic structure and function of the somatic nervous system has been described in numerous physiology, neurology, and neuroscience texts: the reader is referred to two recent books for further information [1,2]. Diabetes affects both the peripheral and the central nervous system (for discussion of the latter see Chapter 5, page 205-208), although most clinical and scientific interest has focused on the periphery because of the devastating effect on nerve fiber integrity. This section provides an overview of the substrate of the somatic nervous system, with a greater emphasis on peripheral than on central structures.

Image

      Fig. 2.1 General organization