Powerfully supported at court by his brother, Claude of Lorraine was no less ably seconded in the field by his son Francis, Count of Aumale, a young hero destined ultimately to surpass even him in glory, and to raise the name of Guise to its apogee of splendour. The constantly-recurring wars with the Emperor yielded him abundant opportunities to display his prowess. In the campaign of 1543 he did good service, until, at the siege of Luxemburg, he was dangerously wounded above the ankle by an arquebuse ball. "Carried, almost without hopes – on account of the fracture of the bones and the injury to the nerves – first to his tent and then to Longwy, five leagues in rear, he owed his recovery to the attention of the King, who sent him his own physicians, and to the care bestowed upon him by his father. And nevertheless, when he suffered signs of pain to escape him during the dressing, the Duke of Guise addressed to him reproaches by which it will be seen that he subsequently profited, saying to him – a noble and stoical maxim – 'That persons of his rank ought not to feel their wounds, but, on the contrary, to take pleasure in building up their reputation on the ruin of their bodies.'" It was in no feather-bed school that the Guises were educated. Nearly at the same time that the Count d'Aumale was hit before Luxemburg, Gaspard de Coligny-Châtillon, then his rival in valour, and at a subsequent day his deadly foe, was severely wounded in the throat at the siege of Binche.
In the war in which these incidents occurred, England was allied with the Emperor against France. Personal motives combined with political irritation to dispose the violent and uxorious Henry VIII. to a rupture with Francis I. Mary of Lorraine, daughter of the Duke of Guise, and widow of Louis of Orleans, duke of Longueville, had been given in marriage to James V. of Scotland, in preference to Henry, who, inflamed by the report of her beauty, had solicited her hand as a pledge of perpetual alliance with France. Dazzling as was the offer of so powerful a sovereign, his anti-catholic acts, and his evil reputation as a husband, deterred the Guises from entertaining it; and Francis I., obeying the dictates of feeling rather than those of prudence, extricated them from a dilemma by alleging a previous promise to the Scottish king. It is said that Henry would then gladly have espoused Louisa, second daughter of the Duke, and that, means being found to elude his pursuit, this second disappointment further augmented his rancorous feelings towards Francis and the house of Guise. However this may have been, the war with England continued subsequently to the conclusion of peace between Francis and Charles – chiefly in Picardy, around Boulogne, which Henry held, and in whose neighbourhood his army was encamped. Some severe skirmishes and partial engagements occurred, and in one of these the Count of Aumale received a wound, probably the severest ever survived by mortal man, from the lance of an English officer. The weapon, according to the description of Ambrose Paré, entered "above the right eye, declining towards the nose, and piercing through on the other side, between the nape and the ear." So violent was the blow that the weapon broke in the head, into which it had penetrated more than half a foot, the entire lance-iron and two fingers' breadth of the staff remaining in the wound. Paré explains the possibility of such a wound, in an age when helmets and visors were in use, by mentioning that the Count always went into action with his face bare.
"Terrible as was the shock," says M. de Bouillé, "it did not unhorse d'Aumale. He still made head against his foes, succeeded in forcing a passage through them, aided by his young and valiant brother Claude, and by de Vieilleville – who, alone of all, had not abandoned him – and rode gloriously into camp. His appearance was frightful; his face, armour, and clothes were deluged with blood. The surgeons, stupified by the depth and gravity of the wound, despaired of cure, and refused to inflict useless sufferings upon the patient. But Ambrose Paré, the King's surgeon, sent by Francis with orders to try every means of saving the hero's life, was not discouraged. Confiding in his skill, and in the firmness of the wounded man, he resolved to attempt an operation, terrible indeed, but admirable for those days, and worthy alone to insure celebrity to him who imagined it. The lance-head was broken off so short, that it was impossible to grasp it with the hand. Taking then a blacksmith's pincers, to draw it out with great force, and assisted, amongst others, by Master Nicolle Lavernan, a very experienced surgeon, he asked the Lorraine prince, in presence of a crowd of officers shuddering with horror, if he would submit to the employment of such means, and would suffer him to place his foot upon his face. 'I consent to everything; proceed,' replied d'Aumale. Nor did his fortitude abandon him for an instant during this cruel operation, which was not effected without fracture of bones, nerves, veins, and arteries, and other parts, and which he endured as if they had only pulled out a hair. The agony extorted from him but the single exclamation – 'Ah! my God!' Transported afterwards in a litter to Pecquigny, he remained for three days in a hopeless state: early on the fifth day more favourable symptoms declared themselves, and nature made such powerful efforts, that the