Advances in Radiation Therapy. Группа авторов

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16Hoeben BA, Bussink J, Troost EG, Oyen WJ, Kaanders JH: Molecular PET imaging for biology-guided adaptive radiotherapy of head and neck cancer. Acta Oncol 2013;52:1257–1271.

17Span PN, Bussink J: Biology of hypoxia. Semin Nucl Med 2015;45:101–109.

18Horsman MR, Mortensen LS, Petersen JB, Busk M, Overgaard J: Imaging hypoxia to improve radiotherapy outcome. Nat Rev Clin Oncol 2012;9:674–687.

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20Wouters BG, Koritzinsky M: Hypoxia signalling through mTOR and the unfolded protein response in cancer. Nat Rev Cancer 2008;8:851–864.

21Meijer TW, Kaanders JH, Span PN, Bussink J: Targeting hypoxia, HIF-1, and tumor glucose metabolism to improve radiotherapy efficacy. Clin Cancer Res 2012;18:5585–5594.

22Leszczynska KB, Foskolou IP, Abraham AG, Anbalagan S, Tellier C, Haider S, et al: Hypoxia-induced p53 modulates both apoptosis and radiosensitivity via AKT. J Clin Invest 2015;125:2385–2398.

23Wijsman R, Kaanders JH, Oyen WJ, Bussink J: Hypoxia and tumor metabolism in radiation oncology: targets visualized by positron emission tomography. Q J Nucl Med Mol Imaging 2013;57:244–256.

24Yaromina A, Krause M, Baumann M: Individualization of cancer treatment from radiotherapy perspective. Mol Oncol 2012;6:211–221.

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30Overgaard J, Hansen HS, Overgaard M, Bastholt L, Berthelsen A, Specht L, et al: A randomized double-blind phase III study of nimorazole as a hypoxic radiosensitizer of primary radiotherapy in supraglottic larynx and pharynx carcinoma. Results of the Danish Head and Neck Cancer Study (DAHANCA) Protocol 5-85. Radiother Oncol 1998;46:135–146.

31Bussink J, van Herpen CM, Kaanders JH, Oyen WJ: PET-CT for response assessment and treatment adaptation in head and neck cancer. Lancet Oncol 2010;11:661–669.

32Lopci E, Grassi I, Chiti A, Nanni C, Cicoria G, Toschi L, et al: PET radiopharmaceuticals for imaging of tumor hypoxia: a review of the evidence. Am J Nucl Med Mol Imaging 2014;4:365–384.

33Krohn KA, Link JM, Mason RP: Molecular imaging of hypoxia. J Nucl Med 2008;49(suppl 2):129S–148S.

34Troost EG, Laverman P, Philippens ME, Lok J, van der Kogel AJ, Oyen WJ, et al: Correlation of [¹⁸F]FMISO autoradiography and pimonidazole (corrected) immunohistochemistry in human head and neck carcinoma xenografts. Eur J Nucl Med Mol Imaging 2008;35:1803–1811.

35Troost EG, Bussink J, Kaanders JH, van Eerd J, Peters JP, Rijken PF, et al: Comparison of different methods of CAIX quantification in relation to hypoxia in three human head and neck tumor lines. Radiother Oncol 2005;76:194–199.

36Shi K, Bayer C, Astner ST, Gaertner FC, Vaupel P, Schwaiger M, et al: Quantitative analysis of [¹8F]FMISO PET for tumor hypoxia: correlation of modeling results with immunohistochemistry. Mol Imaging Biol 2017;19:120–129.

37van Elmpt W, Zegers CM, Reymen B, Even AJ, Dingemans AM, Oellers M, et al: Multiparametric imaging of patient and tumour heterogeneity in non-small-cell lung cancer: quantification of tumour hypoxia, metabolism and perfusion. Eur J Nucl Med Mol Imaging 2016;43:240–248.

38Taylor E, Yeung I, Keller H, Wouters BG, Milosevic M, Hedley DW, et al: Quantifying hypoxia in human cancers using static PET imaging. Phys Med Biol 2016;61:7957–7974.

39Carlin S, Zhang H, Reese M, Ramos NN, Chen Q, Ricketts SA: A comparison of the imaging characteristics and microregional distribution of 4 hypoxia PET tracers. J Nucl Med 2014;55:515–521.

40O’Donoghue JA, Zanzonico P, Pugachev A, Wen B, Smith-Jones P, Cai S, et al: Assessment of regional tumor hypoxia using ¹⁸F-fluoromisonidazole and ⁶⁴Cu(II)-diacetyl-bis(N4-methylthiosemicarbazone) positron emission tomography: comparative study featuring microPET imaging, Po2 probe measurement, autoradiography, and fluorescent microscopy in the R3327-AT and FaDu rat tumor models. Int J Radiat Oncol Biol Phys 2005;61:1493–1502.

41Ljungkvist AS, Bussink J, Kaanders JH, Rijken PF, Begg AC, Raleigh JA, et al: Hypoxic cell turnover in different solid tumor lines. Int J Radiat Oncol Biol Phys 2005;62:1157–1168.

      42Ljungkvist AS, Bussink J, Kaanders JH, van der Kogel AJ: Dynamics of tumor hypoxia measured with bioreductive hypoxic cell markers. Radiat Res 2007;167:127–145.

43Ljungkvist AS, Bussink J, Rijken PF, Raleigh JA, Denekamp J, van der Kogel AJ: Changes in tumor hypoxia measured with a double hypoxic marker technique. Int J Radiat Oncol Biol