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WELCOME TO THE GENOME
A User’s Guide to the Genetic Past, Present, and Future
SECOND EDITION
Rob DeSalle
Institute for Comparative Genomics
American Museum of Natural History
New York
Michael Yudell
Department of Community Health and Prevention
Dornsife School of Public Health
Drexel University
Philadelphia
This second edition first published 2020 © 2020 John Wiley & Sons, Inc.
Edition History John Wiley & Sons 1e, 2005
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Library of Congress Cataloging‐in‐Publication Data
Names: DeSalle, Rob, author. | Yudell, Michael, author.
Title: Welcome to the genome : a user’s guide to the genetic past, present, and future / by Rob DeSalle, Michael Yudell.
Description: Second edition. | Hoboken, NJ : Wiley‐Blackwell, 2020. | Includes bibliographical references and index.
Identifiers: LCCN 2019053496 (print) | LCCN 2019053497 (ebook) | ISBN 9781118107652 (paperback) | ISBN 9781118750315 (adobe pdf) | ISBN 9781118750308 (epub)
Subjects: MESH: Genome, Human | Genomics | Popular Work
Classification: LCC QH447 (print) | LCC QH447 (ebook) | NLM QU 460 | DDC 611/.01816–dc23
LC record available at https://lccn.loc.gov/2019053496 LC ebook record available at https://lccn.loc.gov/2019053497
Cover Design: Wiley
Cover Image: © Mina De La O/Getty Images
We would like to dedicate this book to the Cullman and Korein families,who over the past two decades have generously supported and continue to supportthe expansion of modern genomics at the American Museum of Natural History.
FOREWARD: STILL, THE GENOMIC REVOLUTION
In 2001, the American Museum of Natural History (AMNH) produced a daring and innovative exhibition called the Genomic Revolution. It transcended the usual subject matter and issues that the AMNH addresses with its exhibitions. The show used cutting‐edge interactives and design and covered many up‐to‐date subjects in genomics. Development of the show was as dynamic as the field itself, with revisions to data on genome size and other scientific content required within days before the show opened. We were fortunate that the show also anticipated the announcement of the first draft of the human genome that same year. The production of the show was part of the AMNH’s desire to enter the twenty‐first century with a genomics bang as we also established an institute for comparative genomics and the Ambrose Monell frozen