Poisonous Plants and Phytochemicals in Drug Discovery. Группа авторов. Читать онлайн. Newlib. NEWLIB.NET

Автор: Группа авторов
Издательство: John Wiley & Sons Limited
Серия:
Жанр произведения: Биология
Год издания: 0
isbn: 9781119650256
Скачать книгу
Schultes, R.E., Hofmann, A., and Rätsch, C. (2001). Plants of the Gods – Their Sacred, Healing, and Hallucinogenic Powers, 2e. Rochester: Healing Arts Press.

      63 63 WHO (2004). Neuroscience of Psychoactive Substance Use and Dependence. World Health Organization.

      64 64 Alrashedy, N.A. and Molina, J. (2016). The ethnobotany of psychoactive plant use: a phylogenetic perspective. PeerJ 4: e2546–e2546. https://doi.org/10.7717/peerj.2546.

      65 65 Graziano, S., Orsolini, L., Rotolo, M.C. et al. (2017). Herbal highs: review on psychoactive effects and neuropharmacology. Current Neuropharmacology 15 (5): 750–761. https://doi.org/10.2174/1570159X14666161031144427.

      66 66 Rätsch, C. (2005). The Encyclopedia of Psychoactive Plants: Ethnopharmacology and its Applications. Simon and Schuster.

      67 67 Francis, P.D. and Clarke, C.F. (1999). Angel trumpet lily poisoning in five adolescents: clinical findings and management. Journal of Paediatrics and Child Health 35 (1): 93–95. https://doi.org/10.1046/j.1440‐1754.1999.00328.x.

      68 68 Şanlıdağ, B., Derinöz, O., and Yıldız, N. (2014). A case of pediatric age anticholinergic intoxication due to accidental Datura stramonium ingestion admitting with visual hallucination. The Turkish Journal of Pediatrics 56 (3): 313–315.

      69 69 Pantano, F., Tittarelli, R., Mannocchi, G. et al. (2016). Hepatotoxicity induced by “the 3Ks”: Kava, Kratom and Khat. International Journal of Molecular Sciences 17 (4): 580. https://doi.org/10.3390/ijms17040580.

      70 70 Klietmann, W.F. and Ruoff, K.L. (2001). Bioterrorism: implications for the clinical microbiologist. Clinical Microbiology Reviews 14 (2): 364–381. https://doi.org/10.1128/cmr.14.2.364‐381.2001.

      71 71 Martin, J.W., Christopher, G.W., and Eitzen, E.M. (2007). History of biological weapons: from poisoned darts to intentional epidemics. Medical Aspects of Biological Warfare: 1–20.

      72 72 Gibson, J., Drociuk, D., Fabian, T. et al. (2003). Investigation of a ricin‐containing envelope at a postal facility – South Carolina, 2003. MMWR Morbidity and Mortality Weekly Report 52: 1129–1131.

      73 73 Balali‐Mood, M., Moshiri, M., and Etemad, L. (2013). Medical aspects of bio‐terrorism. Toxicon 69: 131–142. https://doi.org/10.1016/j.toxicon.2013.01.005.

      74 74 Centers for Disease Control and Prevention. (2019). Ricin: epidemiological overview for clinicians. https://emergency.cdc.gov/agent/ricin/clinicians/epidemiology.asp (accessed 4 January 2020).

      75 75 Crompton, R. and Gall, D. (1980). Georgi Markov – death in a pellet. The Medico‐Legal Journal 48 (2): 51–62. https://doi.org/10.1177/002581728004800203.

      76 76 Knight, B. (1979). Ricin – a potent homicidal poison. British Medical Journal 1 (6159): 350–351.

      77 77 Zilinskas, R.A. (1997). Iraq's biological weapons. The past as future? JAMA 278 (5): 418–424.

      78 78 Schep, L.J., Temple, W.A., Butt, G.A., and Beasley, M.D. (2009). Ricin as a weapon of mass terror – separating fact from fiction. Environment International 35 (8): 1267–1271. https://doi.org/10.1016/j.envint.2009.08.004.

      79 79 Tyagi, N., Tyagi, M., Pachauri, M., and Ghosh, P.C. (2015). Potential therapeutic applications of plant toxin‐ricin in cancer: challenges and advances. Tumour Biology 36 (11): 8239–8246. https://doi.org/10.1007/s13277‐015‐4028‐4.

      80 80 Watt, J.M. and Breyer‐Brandwijk, M.G. (1962). The Medicinal and Poisonous Plants of Southern and Eastern Africa, 2e. London: Livingstone.

       Andrew G. Mtewa1,2,3, Chukwuebuka Egbuna4,5, Kennedy J. Ngwira6, Fanuel Lampiao7, Umang Shah8, and Thokozani Kachulu Mtewa9

       1 Division of Biological Chemistry and Drug Discovery, WCAIR, School of Life Sciences, University of Dundee, Dundee, UK

       2 Chemistry Section, Malawi Institute of Technology, Malawi University of Science and Technology, Limbe, Malawi

       3 Pharmbiotechnology and Traditional Medicine Center (PHARMBIOTRAC), Department of Pharmacology, School of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda

       4 Department of Biochemistry, Faculty of Natural Sciences, Chukwuemeka Odumegwu Ojukwu University, Uli, Anambra State, Nigeria

       5 Nutritional Biochemistry and Toxicology Unit, World Bank Africa Centre of Excellence, Centre for Public Health and Toxicological Research (ACE‐PUTOR), University of Port Harcourt, Port Harcourt, Rivers State, Nigeria

       6 Institute of Molecular Science, School of Chemistry, University of Witwatersrand, Johannesburg, South Africa

       7 Africa Centre of Excellency in Public Health and Herbal Medicine, College of Medicine, University of Malawi, Blantyre, Malawi

       8 Department of Pharmaceutical Chemistry, Ramanbhai Patel College of Pharmacy, Charotar University of Science and Technology, Changa, Gujarat, India

       9 Department of Water Resources, Ndata School of Climate and Earth Sciences, Malawi University of Science and Technology, Limbe, Malawi

      CONTENTS

      1  2.1 Introduction 2.1.1 Endophytic Phytotoxins 2.1.2 Secondary Metabolites

      2  2.2 Possible Categorization 2.2.1 Biological Characteristics 2.2.2 Chemical Characteristics

      3  2.3 Currently Available Classification Tools

      4  2.4 Role of Phytotoxin Classification 2.4.1 Drug Discovery 2.4.2 Environmental Monitoring 2.4.3 Phytotoxins, Aquatic Life, and Water Quality 2.4.4 Air Contamination 2.4.5 Food Contamination 2.4.6 Security and Safety Services 2.4.7 Agricultural

      5  2.5