The Evolution of Everything: How Small Changes Transform Our World. Matt Ridley. Читать онлайн. Newlib. NEWLIB.NET

Автор: Matt Ridley
Издательство: HarperCollins
Серия:
Жанр произведения: Историческая литература
Год издания: 0
isbn: 9780007542505
Скачать книгу
before swerving. Alfred Russel Wallace, for instance, co-discovered natural selection and was in many ways an even more radical enthusiast for Darwinism (a word he coined) than Darwin himself. Wallace was not afraid to include human beings within natural selection very early on; and he was almost alone in defending natural selection as the main mechanism of evolution in the 1880s, when it was sharply out of fashion. But then he executed a Lucretian swerve. Saying that ‘the Brain of the Savage [had been] shown to be Larger than he Needs it to be’ for survival, he concluded that ‘a superior intelligence has guided the development of man in a definite direction, and for a special purpose’. To which Darwin replied, chidingly, in a letter: ‘I hope you have not murdered too completely your own and my child.’

      Later, in a book published in 1889 that resolutely champions Darwinism (the title of the book), Wallace ends by executing a sudden U-turn, just like Hume and so many others. Having demolished skyhook after skyhook, he suddenly erects three at the close. The origin of life, he declares, is impossible to explain without a mysterious force. It is ‘altogether preposterous’ to argue that consciousness in animals could be an emergent consequence of complexity. And mankind’s ‘most characteristic and noble faculties could not possibly have been developed by means of the same laws which have determined the progressive development of the organic world in general’. Wallace, who was by now a fervent spiritualist, demanded three skyhooks to explain life, consciousness and human mental achievements. These three stages of progress pointed, he said, to an unseen universe, ‘a world of spirit, to which the world of matter is altogether subordinate’.

      The lure of Lamarck

      The repeated revival of Lamarckian ideas to this day likewise speaks of a yearning to reintroduce mind-first intentionality into Darwinism. Jean-Baptiste de Lamarck suggested long before Darwin that creatures might inherit acquired characteristics – so a blacksmith’s son would inherit his father’s powerful forearms even though these were acquired by exercise, not inheritance. Yet people obviously do not inherit mutilations from their parents, such as amputated limbs, so for Lamarck to be right there would have to be some kind of intelligence inside the body deciding what was worth passing on and what was not. But you can see the appeal of such a scheme to those left disoriented by the departure of God the designer from the Darwinised scene. Towards the end of his life, even Darwin flirted with some tenets of Lamarckism as he struggled to understand heredity.

      At the end of the nineteenth century, the German biologist August Weismann pointed out a huge problem with Lamarckism: the separation of germ-line cells (the ones that end up being eggs or sperm) from other body cells early in the life of an animal makes it virtually impossible for information to feed back from what happens to a body during its life into its very recipe. Since the germ cells were not an organism in microcosm, the message telling them to adopt an acquired character must, Weismann argued, be of an entirely different nature from the change itself. Changing a cake after it has been baked cannot alter the recipe that was used.

      The Lamarckians did not give up, though. In the 1920s a herpetologist named Paul Kammerer in Vienna claimed to have changed the biology of midwife toads by changing their environment. The evidence was flaky at best, and wishfully interpreted. When accused of fraud, Kammerer killed himself. A posthumous attempt by the writer Arthur Koestler to make Kammerer into a martyr to the truth only reinforced the desperation so many non-scientists felt to rescue a top–down explanation of evolution.

      It is still going on. Epigenetics is a respectable branch of genetic science that examines how modifications to DNA sequences acquired early in life in response to experience can affect the adult body. There is a much more speculative version of the story, though. Most of these modifications are swept clean when the sperm and egg cells are made, but perhaps a few just might survive the jump into a new generation. Certain genetic disorders, for example, seem to manifest themselves differently according to whether the mutant chromosome was inherited from the mother or the father – implying a sex-specific ‘imprint’ on the gene. And one study seemed to find a sex-specific effect on the mortality of Swedes according to how hungry their grandparents were when young. From a small number of such cases, none with very powerful results, some modern Lamarckians began to make extravagant claims for the vindication of the eighteenth-century French aristocrat. ‘Darwinian evolution can include Lamarckian processes,’ wrote Eva Jablonka and Marion Lamb in 2005, ‘because the heritable variation on which selection acts is not entirely blind to function; some of it is induced or “acquired” in response to the conditions of life.’

      But the evidence for these claims remains weak. All the data suggest that the epigenetic state of DNA is reset in each generation, and that even if this fails to happen, the amount of information imparted by epigenetic modifications is a minuscule fraction of the information imparted by genetic information. Besides, ingenious experiments with mice show that all the information required to reset the epigenetic modifications themselves actually lies in the genetic sequence. So the epigenetic mechanisms must themselves have evolved by good old Darwinian random mutation and selection. In effect, there is no escape to intentionality to be found here. Yet the motive behind the longing to believe in epigenetic Lamarckism is clear. As David Haig of Harvard puts it, ‘Jablonka and Lamb’s frustration with neo-Darwinism is with the pre-eminence that is ascribed to undirected, random sources of heritable variation.’ He says he is ‘yet to hear a coherent explanation of how the inheritance of acquired characters can, by itself, be a source of intentionality’. In other words, even if you could prove some Lamarckism in epigenetics, it would not remove the randomness.

      Culture-driven genetic evolution

      In fact, there is a way for acquired characteristics to come to be incorporated into genetic inheritance, but it takes many generations and it is blindly Darwinian. It goes by the name of the Baldwin effect. A species that over many generations repeatedly exposes itself to some experience will eventually find its offspring selected for a genetic predisposition to cope with that experience. Why? Because the offspring that by chance happen to start with a predisposition to cope with that circumstance will survive better than others. The genes can thereby come to embody the experience of the past. Something that was once learned can become an instinct.

      A similar though not identical phenomenon is illustrated by the ability to digest lactose sugar in milk, which many people with ancestors from western Europe and eastern Africa possess. Few adult mammals can digest lactose, since milk is not generally drunk after infancy. In two parts of the world, however, human beings evolved the capacity to retain lactose digestion into adulthood by not switching off genes for lactase enzymes. These happened to be the two regions where the domestication of cattle for milk production was first invented. What a happy coincidence! Because people could digest lactose, they were able to invent dairy farming? Well no, the genetic switch plainly happened as a consequence, not a cause, of the invention of dairy farming. But it still had to happen through random mutation followed by non-random survival. Those born by chance with the mutation that caused persistence of lactose digestion tended to be stronger and healthier than their siblings and rivals who could digest less of the goodness in milk. So they thrived, and the gene for lactose digestion spread rapidly. On closer inspection, this incorporation of ancestral experience into the genes is all crane and no skyhook.

      So incredible is the complexity of the living world, so counterintuitive is the idea of boot-strapped, spontaneous intricacy, that even the most convinced Darwinian must, in the lonely hours of the night, have moments of doubt. Like Screwtape the devil whispering in the ear of a believer, the ‘argument from personal incredulity’ (as Richard Dawkins calls it) can be very tempting, even if you remind yourself that it’s a massive non sequitur to find divinity in ignorance.

       4

       The Evolution of Genes

      For certainly the elements of things do not collect

      And order their formations by their cunning intellect,

      Nor