Invested with his new dignities, whose importance his sagacity fully appreciated, Guise, with the least possible delay, set out for Compiègne, which, since the recent disasters of the French arms, was a frontier town. Those disasters, he felt, could be effectually repaired only by a brilliant feat of arms, at once useful to the state, and flattering to the national pride. Upon such a one he resolved. Calais, now upwards of two centuries in possession of the English, to the great humiliation of France, was the object of destined attack. Skilled in the stratagems of war, the Duke contrived, by a series of able manœuvres, to avert suspicion of his real design, until, on the 1st January 1558, he suddenly appeared before the ramparts of Calais. The siege that ensued has been often narrated. It terminated, after an obstinate resistance, in the capitulation of the garrison, which had scarcely been executed, when an English fleet appeared off the port, bearing succours that came too late. The triumph excited indescribable astonishment and joy throughout France. It was a splendid revenge for the defeat of St Quintin, and produced a marked change in the sentiments of several foreign potentates, who believed that reverse to have prostrated the French power for some time to come. The Grand Signior offered the co-operation of his fleet, and the German princes hastened, with redoubled good-will, the levies that had been demanded of them. Pope Paul IV., when congratulating the French ambassador, pronounced the highest eulogiums on Guise, and declared the conquest of Calais preferable to that of half England. At court, the partisans of the Constable were in dismay, and tried to lessen the merit of the victor by attributing its success to the adoption of a plan sketched by Coligny. But even if this were true, the merit of the execution was all the Duke's own. Upon the heels of this triumph, quickly followed the capture of Guines and the evacuation by the English of the castle of Hames, their last possession in the county of Oye. "In less than a month," says M. de Bouillé, "Francis of Lorraine had accomplished the patriotic but difficult enterprise so often and fruitlessly attempted during two centuries, and had cancelled the old proverb applied in France, in those days, to generals of slight merit, of whom it was derisively said, 'He will never drive the English out of France.'"
Henry II., accompanied by the Dauphin, the Cardinals of Lorraine and Guise, and several nobles of the court, made a journey to Calais, which he entered with great pomp. The object of this expedition was to sustain the courage and zeal of the troops, who endured much fatigue and hardship, in that inclement season and in the midst of the marshes. The King also wished to testify his gratitude to his lieutenant-general, showing him great confidence, referring to him all who requested audience on business, and presenting him, in the most flattering terms, with a house in Calais. The Duke returned with Henry to Paris, where great feasts and rejoicings were held in his honour, and, on occasion of the Dauphin's marriage with Mary Queen of Scots, which shortly followed, Guise filled, in the absence of Montmorency, the office of grand-master, which he long had coveted. Concurrently, however, with this great apparent favour, Henry was secretly uneasy at the power and pretensions of the family of Guise, and maintained a constant and confidential correspondence with their inveterate enemy the Constable de Montmorency. On the other hand the Guises were on their guard, labouring to countermine and defeat the intrigues levelled against them. Urged on by his brother, and feeling that, in their position, if they did not advance they must recede, the Duke directed all his efforts to an effectual concentration in his own hands of the entire military power of the kingdom. Should he fail in this, he at least was resolved to leave none in those of his rivals. By this time the progress of the Reformed religion in France had attracted great attention. It was an abomination in the eyes of Henry; and of this the Duke and Cardinal took advantage to work the downfall of d'Andelot, brother of Coligny, and colonel-general of the French infantry, the only military commander who at that moment caused them any uneasiness. Accused of heresy, and summoned before the King, who received him kindly, and, expecting he would so reply as to disconcert his enemies, "commanded him to declare, in presence of all the court, his belief with respect to the holy sacrifice of mass; d'Andelot proudly replied that his gratitude for the King's favours doubtless rendered entire devotedness incumbent upon him, but that his soul belonged to God alone; that, enlightened by the torch of Scripture, he approved the doctrines of Calvin, and considered mass a horrible profanation and an abominable invention of man." Furious at what he deemed a blasphemy, the King, who was at supper, snatched a basin from the table and hurled it at d'Andelot; but it struck the Dauphin. He was then tempted, says one of his historians, to pierce the offender with his sword, but finally contented himself with sending him to prison, and the post of colonel-general was bestowed upon Montluc, an ex-page of Guise's grandfather, and a devoted partisan of the house of Lorraine. This brave Gascon officer at first scrupled to accept it, for he feared to incur the hatred of the Colignys and the Constable. Wily and wary, like most of his countrymen, he declared himself willing to serve as a private soldier under the Duke, but modestly declined the command offered him. The King insisting, he alleged a dysentery, as rendering him incapable of the needful activity. This and other objections being overruled, he took possession of his important command, and speedily proved himself worthy to hold it – notably at the siege of Thionville on the Moselle. This fortress, one of the strongest the Imperialists owned, was defended by Jean de Caderebbe, a brave gentleman of Brabant, at the head of three thousand picked men. The Dukes of Guise and Nevers, and Marshal Strozzi, were the leaders of the besieging army; Montluc joined them on the eve of the opening of the batteries, and did excellent service. On the fifteenth day of the siege, Guise was in the trenches, talking to Strozzi, on whose shoulder his hand rested, when the Marshal was struck by an arquebuse ball, a little above the heart. On feeling himself hit, "Ah! tête Dieu, Monsieur," exclaimed this brave and able general, "the King loses to-day a good servant, and your Excellency also." He did himself no more than justice. Guise was deeply affected, but, repressing his emotion, he tried to fix Strozzi's thoughts on religion. The veteran's death was less exemplary than his life; he died in profession of unbelief; and Guise, much scandalised, but perhaps doubly furious at the thought that the soul as well as the body of his old comrade had perished by the sudden manner of his death, prosecuted the siege with fresh ardour, eager for revenge, and suppressing for the moment, as far as he was able, the disastrous news, which could not but produce a most unfavourable impression. Valiantly seconded by Montluc and Vieilleville, on the 22d June, two days after Strozzi's death, he received the capitulation of the garrison. His triumph was well earned. Besides the exhibition, throughout the siege, of the genius and inventive resource that constitute a general of the highest order, he had toiled and exposed himself like a mere subaltern, constantly under fire, personally superintending the pioneers and artillerymen, and rarely sleeping; so that it was no wonder (considering he had not had a single night's rest during the operations against Thionville) that on the 1st July, when preparing for the siege of the rich little town of Arlon, he complained of being very drowsy, and left Montluc to invest the place – himself retiring to bed in a cottage, and giving orders to let him sleep till he awoke of himself. "It is very quick work," he observed, crossing himself, when he was the next day informed, in reply to his inquiry whether the batteries had opened fire, that Montluc had surprised and taken the place in the night.
Whilst Guise was thus not only rendering great services himself, but bringing forward leaders whose exploits honoured the French arms, in other quarters affairs went less favourably for France. Near Dunkirk, Marshal Thermes was beaten and taken prisoner, and Guise, whose frequent lot it was to repair the blunders or misfortunes of less capable generals, marched to Picardy; on the frontier of which province, at a grand review passed by Henry II., the Duke's son and successor, Henry, Prince of Joinville, then but eight years old, appeared for the first time in public, with his cousin, the Count of St Vallier, son of the Duke d'Aumale. Accompanied by their preceptors and some other gentlemen, and mounted on ponies, they rode through the ranks, until they reached the troops commanded by Montluc. "Cà, çà, my little princes," exclaimed that brave captain, "dismount; for I was brought up in the house of which you are issue, which is the house of Lorraine, where I was page, and I will be the first to put arms in your hands." The two cousins dismounted, and Montluc, taking off the little silken robons that covered their shoulders, placed a pike in the hand of each of them. "I hope," he said, "that God will give you grace to resemble your fathers, and that I shall have brought you good fortune by being the first to invest you with arms. To me they have hitherto been favourable. May God render you as brave as you are handsome, and sons of very good and generous fathers." After this species of martial baptism, the two children,