Table of Contents
1 Cover
5 Preface
8 Part 1: CORONARY ARTERY DISEASE 1 Non-ST-Segment Elevation Acute Coronary Syndrome Appendix 1. Complex angiographic disease- Moderate disease progression Appendix 2. Women and ACS, elderly patients and ACS, CKD Appendix 3. Bleeding, transfusion, patients on chronic warfarin or NOAC, gastrointestinal bleed Appendix 4. Antiplatelet and anticoagulant therapy Appendix 5. Difference between plaque rupture and plaque erosion Appendix 6. Spontaneous coronary artery dissection Appendix 7. Harmful effects of NSAIDs and cyclooxygenase-2 inhibitors in CAD Appendix 8. Additional ideas on the physiology of hs-troponin-Role of hs-troponin in primary prevention QUESTIONS AND ANSWERS References 2 ST-Segment Elevation Myocardial Infarction 1. DEFINITION, REPERFUSION, AND GENERAL MANAGEMENT 2. STEMI COMPLICATIONS Appendix 1. Out-of-hospital cardiac arrest: role of early coronary angiography and therapeutic hypothermia QUESTIONS AND ANSWERS References Other acute therapies Early discharge Prognosis ICD Shock (+ SHOCK trial and CULPRIT-SHOCK trial, references 69 and 73) RV shock (+ reference 89 above) Mechanical complications Arrhythmias Aneurysm and pseudo-aneurysm Post-MI pericarditis LV thrombus Prognosis Cardiac arrest Note 3 Stable Ischemic Heart Disease and Approach to Chronic Chest Pain Appendix 1. Notes on various surgical grafts Appendix 2. Coronary vasospasm (variant angina, Prinzmetal angina) Appendix 3. Microvascular endothelial dysfunction Appendix 4. Women with chest pain and normal coronary arteries Appendix 5. Diagnostic strategy for ischemia with non-obstructed coronary arteries (INOCA) Appendix 6. Myocardial bridging Appendix 7. Coronary collaterals, chronic total occlusion Appendix 8. Hibernation, stunning, ischemic preconditioning QUESTIONS AND ANSWERS References
9
Part 2: HEART FAILURE (CHRONIC AND ACUTE HEART FAILURE, SPECIFIC CARDIOMYOPATHIES, AND PATHOPHYSIOLOGY)
4 Heart Failure
DEFINITION, TYPES, CAUSES, AND DIAGNOSIS OF HEART FAILURE
1. DEFINITION AND TYPES OF HEART FAILURE
I. Heart failure is diagnosed clinically, not by echocardiography
II. After HF is defined clinically, echocardiography is used to differentiate the three major types of HF
2. CAUSES OF HEART FAILURE
I. Systolic HF or HF with reduced EF (HFrEF)
II. HF with preserved EF (HFpEF)
III. Right HF
3. DIAGNOSTIC TESTS
I. Echocardiography
II. BNP
III. ECG
IV. Coronary angiography and other ischemic tests
V. Diastolic stress testing
VI. Endomyocardial biopsy
VII. Cardiac MRI
CHRONIC TREATMENT OF HEART FAILURE
1. TREATMENT OF SYSTOLIC HEART FAILURE
I. Treat the underlying etiology: target BP and CAD
II. Value of revascularization