10 4 How to Section 29 How to Interpret EUS‐FNA Cytology Introduction Technical quality of EUS biopsy material Quality of the interpretation Integration of pathologic and clinical information 30 How to do Mediastinal FNA 31 How to do Pancreatic Mass FNA Introduction The technique 32 How to do Pancreatic Cyst FNA Introduction Technique (Video 32.1) Summary 33 How to do Pancreatic Pseudocyst Drainage Introduction Patient selection Requisite instruments and accessories Assessment of the pseudocyst by EUS prior to drainage Technique for placement of plastic endoprosthesis Technique for lumen‐apposing metal stent placement Post‐procedure follow‐up 34 How to do EUS‐guided Pancreatic Cyst Chemoablation Background Pretreatment evaluation Patient selection Technical aspects of the procedure Postoperative care and follow‐up Conclusions References 35 How to do Celiac Plexus Block Introduction Technique (Video 35.1) Complications 36 How to Place Fiducials for Radiation Therapy Introduction Equipment Techniques Periprocedural care 37 How to Inject Chemotherapeutic Agents 38 How to do EUS‐guided Pelvic Abscess Drainage Introduction Patient preparation Devices and accessories Procedural technique Clinical outcomes Technical limitations Conclusions 39 How to do Doppler Probe EUS for Bleeding Background and equipment Practical application of DopUS probe Conclusions 40 How to do Endoscopic Ultrasound‐guided Portal Pressure Gradient Measurement Introduction Endoscopic ultrasound‐guided PPGM technique References 41 How to do Endoscopic Ultrasound‐guided Liver Biopsy Indications and contraindications EUS‐LB technique Postprocedure recovery after EUS‐LB Adverse effects Conclusions References 42 How to do EUS‐guided Treatment of Gastric Varices Introduction Technique (Video 42.1) Complicatons 43 How to do EUS‐guided Arterial Embolization Background Technique Postprocedural management and complications References 44 How to do EUS‐guided Radiofrequency Ablation of Pancreatic Neuroendocrine Tumors Introduction Methods for EUS‐guided RFA Indications Results for EUS‐guided RFA studies Conclusion