95 In Stephani Artis Med. Princip. ii. p. 253.
96 De Lapidibus, lib. ii. p. 131.
97 J. J. Wecker, De Secretis.
98 I took the trouble to search for this passage in Jac. Hollerii lib. de morbis internis, Parisiis 1711, 4to, but I could not find it, though the beginning of the book treats expressly of head-aches.
99 Magia Naturalis, lib. vii.
100 Kircheri Magnes, sive De Arte Magnetica, lib. iii. c. i.
101 P. Borrelli, Hist. et Observ. Medico-physic. cent. 4. obs. 75.
102 Observations sur l’usage de l’aimant en médecine, par MM. Audry et Thouret.
SECRET POISON.
Under this name are generally understood all poisons which can be administered imperceptibly, and which gradually shorten the life of man, like a lingering disease. They were not first discovered in the 17th century in France and Italy as many believe, but were known to the ancient Greeks and Romans, by whom they were used. I must however allow, that they were never prepared with more art at any period, or in any country, or employed oftener and with more success, than they were in these countries, and at that time. If it be true that they can be prepared in such a manner as to occasion death at a certain period previously determined, or that the person to whom they are given will die within a certain time limited, it must be confessed that the ancient poisoners have been far exceeded by the modern. But this advantage will be considered as scarcely possible, when one reflects upon the many variable circumstances which have an influence on the operation of medicines and poisons; and it has often happened that a company have swallowed the same poison, at the same time, and in the same quantity, some of whom have died sooner and some later, while some have survived. Thus died Pope Alexander VI. in the year 1503, and Cæsar Borgia recovered without any loss of health, though, by the bottles being changed through mistake, he drank of the poison that had been prepared for the other guests alone. At any rate, I am of opinion that the celebrated Tophania, when she engaged to free wives from disagreeable husbands within stated weeks and days, must have had certain and very accurate information respecting their constitution and manner of living, or, as the physicians say, their idiosyncrasy.
Some physicians have doubted respecting secret poison103; and others have only denied that its effects can with certainty be regulated to a fixed time104. I agree in opinion with the latter; but the former can be confuted by many examples both of ancient and modern times; for that the ancients were acquainted with this kind of poison, can be proved by the testimony of Plutarch, Quintilian, and other respectable authors. We are told by Plutarch, that a slow poison, which occasioned heat, a cough, spitting of blood, consumption, and a weakness of intellect, was administered to Aratus of Sicyon105; and Quintilian in his Declamations, speaks of this poison in such a manner as proves that it must then have been well known106. It cannot be said that such an invention was too great for that period, or that it required more knowledge of chemistry than any one possessed; for the Indians in America are acquainted with a most perfect poison of this kind, and can employ it with so much skill, that the person to whom it is given cannot guard against the treachery, even with the utmost precaution, but infallibly dies, though in a lingering manner, often after the expiration of some years107.
Theophrastus speaks of a poison which could be moderated in such a manner as to have effect in two or three months, or at the end of a year, or two years; and he remarks that the death, the more lingering it was, became the more miserable. This poison was prepared from aconitum, a plant which, on that account, people were forbidden to have in their possession, under pain of capital punishment108. He relates also, that Thrasyas had discovered a method of preparing from other plants a poison which, given in small doses of a drachm, occasioned an easy but certain death, without any pain, and which could be kept back for a long time without causing weakness or corruption. This Thrasyas, whose scholar Alexias carried the art still further, was a native of Mantinea, a city in Arcadia, and is celebrated by Theophrastus on account of his abilities, and particularly his knowledge of botany; but those are mistaken who ascribe to him the discovery of secret poison.
This poison was much used at Rome about two hundred years before the Christian æra. As several persons of distinction died the same year at that period, and of the like distemper, an inquiry being made into the cause, a maid-servant gave evidence against some ladies of the first families, who, she said, prepared and distributed poison; and above a hundred and fifty of them were convicted and punished109. As so many had learnt this destructive art, it could not be suppressed; and we find sufficient proofs in the Roman history that it was continually preserved. Sejanus caused such a secret poison to be administered by an eunuch to Drusus, who gradually declined afterwards, as by a consumptive disorder, and at length died110. Agrippina, being desirous of getting rid of Claudius, but not daring to despatch him suddenly, and yet wishing not to leave him sufficient time to make new regulations respecting the succession to the throne, made choice of a poison which should deprive him of his reason, and gradually consume him. This she caused to be prepared by an expert poisoner, named Locusta, who had been condemned to death for her infamous actions, but saved that she might be employed as a state engine. The poison was given to the emperor in a dish of mushrooms; but as, on account of his irregular manner of living, it did not produce the desired effect, it was assisted by some of a stronger nature111. This Locusta prepared also the poison with which Nero despatched Britannicus, the son of Agrippina, whom his father Claudius wished to succeed him on the throne. As this poison occasioned only a dysentery, and was too slow in its operation, the emperor compelled Locusta by blows, and by threatening her with death, to prepare in his presence one more powerful. It was first tried on a kid; but as the animal did not die till the end of five hours, she boiled it a little longer, until it instantaneously killed a pig to which it had been given, and this poison despatched Britannicus as soon as he had tasted it112. For this service the emperor pardoned Locusta, rewarded her liberally, and gave her pupils whom she was to instruct in her art, in order that it might not be lost.
The art of preparing this poison must have been well understood also at Carthage. When M. Attilius Regulus, the Roman general, who had been taken by the Carthaginians, was sent to Rome to propose to the senate that the Carthaginian prisoners might be restored in exchange for him, he prevented this negotiation, because he knew that a poison had been administered to him, by which the state would soon be deprived of his services. He returned, therefore, to Carthage, in compliance with the promise he had made to the enemy, who put him to death with the most