Table of Contents
1 COVER
4 PREFACE
7 SECTION 1: THE STRUCTURE OF THE CELL 1 A LOOK AT CELLS AND TISSUES ONLY TWO TYPES OF CELL VIRUSES ORIGIN OF EUKARYOTIC CELLS CELL SPECIALIZATION IN ANIMALS STEM CELLS AND TISSUE REPLACEMENT THE CELL WALL MICROSCOPES REVEAL CELL STRUCTURE FLUORESCENCE MICROSCOPY FURTHER READING REVIEW QUESTIONS THOUGHT QUESTION 2 MEMBRANES AND ORGANELLES BASIC PROPERTIES OF CELL MEMBRANES ORGANELLES BOUNDED BY DOUBLE‐MEMBRANE ENVELOPES ORGANELLES BOUNDED BY SINGLE MEMBRANES THE CONNECTED CELL FURTHER READING REVIEW QUESTIONS THOUGHT QUESTION
8
SECTION 2: THE MOLECULAR BIOLOGY OF THE CELL
3 DNA STRUCTURE AND THE GENETIC CODE
THE STRUCTURE OF DNA
DNA AS THE GENETIC MATERIAL
PACKAGING OF DNA MOLECULES INTO CHROMOSOMES
THE GENETIC CODE
FURTHER READING
REVIEW QUESTIONS
THOUGHT QUESTION
4 DNA AS A DATA STORAGE MEDIUM
DNA REPLICATION
PROTEINS OPEN UP THE DNA DOUBLE HELIX DURING REPLICATION
BIOCHEMISTRY OF DNA REPLICATION
DNA REPAIR AFTER REPLICATION
GENE STRUCTURE AND ORGANIZATION IN EUKARYOTES
GENE NOMENCLATURE
FURTHER READING
REVIEW QUESTIONS
THOUGHT QUESTION
5 TRANSCRIPTION AND THE CONTROLOF GENE EXPRESSION
STRUCTURE OF RNA
RNA POLYMERASE
GENE NOTATION
BACTERIAL RNA SYNTHESIS
CONTROL OF BACTERIAL GENE EXPRESSION
EUKARYOTIC RNA SYNTHESIS
CONTROL OF EUKARYOTIC GENE EXPRESSION
NONCODING RNAs AND THE CONTROL OF EUKARYOTIC GENE EXPRESSION
FURTHER READING
REVIEW QUESTIONS
THOUGHT QUESTION
6 MANUFACTURING PROTEIN
ATTACHMENT OF AN AMINO ACID TO ITS tRNA
THE RIBOSOME
BACTERIAL PROTEIN SYNTHESIS
EUKARYOTIC PROTEIN SYNTHESIS IS A LITTLE MORE COMPLEX
ANTIBIOTICS AND PROTEIN SYNTHESIS
PROTEIN DESTRUCTION
FURTHER READING
REVIEW QUESTIONS
THOUGHT QUESTION
7 PROTEIN STRUCTURE
NAMING PROTEINS
POLYMERS OF AMINO ACIDS
OTHER AMINO ACIDS ARE FOUND IN NATURE
THE THREE‐DIMENSIONAL STRUCTURES OF PROTEINS
LEVELS OF COMPLEXITY
PROSTHETIC GROUPS