Dynamic Combinatorial Chemistry. In Drug Discovery, Bioorganic Chemistry, and Materials Science - Benjamin Miller L.
| Автор: | Benjamin Miller L. |
| Издательство: | John Wiley & Sons Limited |
| Серия: | |
| Жанр произведения: | Прочая образовательная литература |
| Год издания: | 0 |
| isbn: | 9780470551547 |
Effective techniques for applying Dynamic Combinatorial Chemistry In a relatively short period, Dynamic Combinatorial Chemistry (DCC) has grown from proof-of-concept experiments in a few isolated labs to a broad conceptual framework with applications to an exceptional range of problems in molecular recognition, lead compound identification, catalyst design, nanotechnology, polymer science, and others. Bringing together a group of respected experts, this overview explains how chemists can apply DCC and fragment-based library methods to lead generation for drug discovery and molecular recognition in bioorganic chemistry and materials science. Chapters cover: Basic theory Approaches to binding in proteins and nucleic acids Molecular recognition Self-sorting Catalyst discovery Materials discovery Analytical chemistry challenges A comprehensive, single-source reference about DCC methods and applications including aspects of fragment-based drug discovery, this is a core reference that will spark the development of new solutions and strategies for chemists building structure libraries and designing compounds and materials.